Nitin (Akshay Kumar) and Ram (Suniel Shetty) are only lucky in love - otherwise their life is a big zero as is their bank balance! But now their rich girlfriends - Anjali (Katrina Kaif) and Manpreet (Sameera Reddy) have given them an ultimatum - earn enough money so that we can elope or forget us forever ...Broke and desperate Nitin and Ram need to make big money and fast.

They hit upon an audacious plan - to kidnap Moolchandji - the spoilt dog of rich bitch Archana (Archana Puran Singh).  But Moolchandji runs away, and the police think it's Nitin who's been kidnapped. As the guys try to get their hands on the ransom money, they encounter assorted characters like a Chinese Don, a hired assassin, an ACB officer, a club dancer, an ambassador, a young frustrated wife, a letch, a drunken waiter and a dead body nobody wants....what happens next is De Dana Dan... full of so many twists and turns that you'll turn giddy with laughter! De Dana Dan - full of masti and madness!!